Welcome to the Sia Lab

Our lab focuses on using microfluidics for two different applications: tissue engineering and point-of-care diagnostics.

3D Tissue Engineering

We focus on the following core question: how do cells form tissues in three dimensions? We answer this question by precisely controlling cellular microenvironments, using advanced techniques in spatial positioning of cells, extracellular matrix, and growth factors. Ultimately, we aim to have the ability to rationally design tissues and organs and construct them from the ground up, cell by cell.

Point-of-Care Diagnostics

Our second major focus is to use the powerful techniques of MEMS and microfluidics to build low-cost handheld devices for performing sophisticated medical tests on a small credit card-sized chip. Our ultimate goal is to deploy these devices in remote settings in order to improve the health of people in developing countries.

Latest News

Dr. Sia gives plenary talks at the NIH/AID International Research in Infectious Diseases Annual Meeting in Bethesda, and the ISLH 2012 in Nice, France, and invited talks in AIP Industrial Physics Forum in Trieste, Italy, and Emerging Concepts in Cancer meeting in Berlin, Germany. 4/2012

Review published in Lab on a Chip on "Commercialization of microfluidic point-of-care diagnostic devices." 2/2012

mChip technology recognized by 2011 Wall Street Journal Innovation Awards (Medical Devices category). 11/2011

mChip project nominated for a $2 million "Saving Lives at Birth" transition award from a consortium led by USAID. 9/2011

Prof. Sia and Curtis Chin provide a news and views article in Nature Chemistry on expanding the glucose meters to detect a range of other analytes. 8/2011

A multi-year effort on developing and field testing a new point-of-care diagnostics device in sub-Saharan Africa has been published by Nature Medicine. This work is led by Curtis Chin, Tassaneewan Laksanasopin, Yukkee Cheung and others in the Sia Lab, in collaboration with Claros Diagnostics, Columbia ICAP and three NGO partners in Rwanda (Projet San Francisco, Projet Ubuzima, and Academic Medical Center of the University of Amsterdam). Covered by Nature, JAMA, NPR, The Washington Post, Technology Review, Guardian, Voice of America, CBC, AFP, Rwandan News Agency, BBC News, and Le Figaro. Also see Nature Medicine video and story from the Engineering School. 8/2011