Sia Lab at Columbia University

Publications

2008

23. H. Parsa, C. D. Chin, P. Mongkolwisetwara, B. W. Lee, J. J. Wang, and S. K. Sia, Effect of Volume- and Time-Based Constraints on Capture of Analytes in Microfluidic Heterogeneous Immunoassays, in press, Lab on a Chip. (2008).

22. B. M. Gillette, J. A. Jensen, B. Tang, G. J. Yang, A. Bazargan-Lari, M. Zhong and S. K. Sia, In situ collagen assembly for integrating microfabricated three-dimensional cell-seeded matrices, 7, 636 - 640, Nature Materials. (2008).
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[This article was chosen as the cover article, and accompanied by a News and Views article. full-text (html)]

21. J. Lii, W.J. Hsu, H. Parsa, A. Das, R. Rouse and S.K. Sia, Real-Time Microfluidic System for Studying Mammalian Cells in 3D Microenvironments, 80 (10), 3640–3647, Anal. Chem. (2008).
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[This article was covered in Chemical and Engineering News. full-text (jpg) ]

20. C.D. Chin, K. Khanna and S.K. Sia, A microfabricated porous collagen-based scaffold as prototype for skin substitutes, 10, 459-67, Biomed. Microdev. (2008).
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2007

19. S.K. Sia, B.M. Gillette and G.J. Yang, Synthetic tissue biology: tissue engineering meets synthetic biology, 81, 354-61, Embryo Today (2007).
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18. Y.K. Cheung, B.M. Gillette, M. Zhong, S. Ramcharan and S.K. Sia, Direct patterning of composite biocompatible microstructures using microfluidics, Lab on a Chip, 7, 574-579 (2007).
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[This article was covered in Chemical Science. full-text (html) ]

17. S.K. Sia, Developing diagnostics, Chemical Technology (2007).
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16. C.D. Chin, V. Linder and S.K. Sia, Lab-on-a-chip devices for global health, Lab on a Chip, 7, 41-57 (2007).
[This work was chosen as the cover article.]
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2006

15. J. Lii, W. Hsu, S. Lee and S.K. Sia, Microfluidics, Kirk-Othmer Encyclopedia of Chemical Technology (2006).

Pre-Columbia Publications

14. P. Garstecki, M. Fuerstman, M. A. Fischbach, S.K. Sia and George M. Whitesides, Mixing with bubbles: a practical technology for use with portable microfluidic devices, Lab on a Chip, 6, 207-212 (2006).

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13. N. Damean, S.K. Sia, V. Linder, M. Navrolyansky and G.M. Whitesides, Space- and time-resolved spectrophotometry in microsystems, Proc. Natl. Acad. Sci., 102:10035-10039 (2005).
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12. D.B. Weibel, M. Kruithof, S. Potenta, S.K. Sia, A. Lee and G.M. Whitesides, Torque-actuated pressure valves for microfluidics, Anal. Chem., 77:4726-4733 (2005).
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11. V. Linder, S.K. Sia and G.M. Whitesides, Reagent-loaded cartridges for valveless and automated fluid delivery in microfluidic devices, Anal. Chem., 77:64-71 (2005).
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10. D. Ryan, B.A. Parviz, V. Linder, V. Semetey, S.K. Sia, J. Su, M. Mrksich and G.M. Whitesides, Patterning multiple aligned self-assembled monolayers using light, Langmuir, 20:9080-9088 (2004).
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9. S.K. Sia, V. Linder, B.A. Parviz, A. Siegel and G.M. Whitesides, An integrated approach to a low-cost and portable immunoassay for resource-poor settings, Angew. Chem. Int. Ed., 43:498-502 (2004).
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[This work was selected as Editor's Choice in Science (pdf) and featured by Science News (link).]

8. S.K. Sia and G.M. Whitesides, Microfluidic devices based on poly(dimethylsiloxane) for biological studies, Electrophoresis, 24:3563-3576 (2003).
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7. S.K. Sia and P.S. Kim, Protein grafting of an HIV-1 inhibiting epitope, Proc. Natl. Acad. Sci., 100, 9756-9761 (2003).
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6. S.K. Sia, P.A. Carr, A.G. Cochran, V.N. Malashkevich and P.S. Kim, Short, constrained alpha-helical peptides that inhibit HIV-1 entry, Proc. Natl. Acad. Sci., 99, 14664-14669 (2002).
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[This work was classified as a "Must Read" article by Faculty of 1000 (link).]

5. S.K. Sia and P.S. Kim, A designed protein featuring packing left and right-handed helices, Biochemistry, 40, 8981-89 89 (2001).
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4. S.K. Sia, M.X. Li, L. Spyracopoulos, S.M. Gagne, W. Liu, J.A. Putkey, and B.D. Sykes, Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain, J. Biol. Chem., 272(29):18216-21 (1997).
[This work was featured as research news in Nature Biotechnology, Sept 1997 (issue 15, p. 826).]
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3. L. Spyracopoulos, M.X. Li, S.K. Sia, S.M.Gagne, M. Chandra, R.J. Solaro, and B.D. Sykes, Calcium-induced structural transition in the regulatory domain of human cardiac troponin C, Biochemistry, 36(40):12138-46 (1997).
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2. S.C. Mosimann, M.M. Cherney, S. Sia, S. Plotch, and M.N. James, Refined X-ray crystallographic structure of the poliovirus 3C gene product, J. Mol. Biol., 273(5):1032-47 (1997).
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1. D.M. Pinto, E.A. Arriaga, S. Sia, Z. Li, and N.J. Dovichi, Solid-phase fluorescent labeling reaction of picomole amounts of insulin in very dilute solutions and their analysis by capillary electrophoresis, Electrophoresis, 16(4):534-40 (1995).
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