On Friday, August 21st @ 12:00PM EDT, we welcome Professor Christoph Juchem from Columbia University as he presents, “In Vivo Magnetic Resonance Spectroscopy - A Tool for Translational and Clinical Research.”

ABOUT THE AUGUST 21 WEBINAR

Magnetic resonance spectroscopy (MRS) allows the detection and quantification of chemical compounds from localized regions in living tissue, e.g., the brain, in a noninvasive fashion. The repertoire of measurable compounds along with the quantitative character of the derived information makes MRS a versatile tool for the study of metabolism and function and, moreover, the identification of virtually all disorders with a metabolic signature. Reliable extraction of biochemical information, however, critically relies on optimal experimental conditions and procedures as well as processing and quantification strategies. In my talk, I will discuss commonly encountered challenges of in vivo MRS along with specific solutions developed in our laboratory. I will present a comprehensive framework of 1) methods for experiment setup and optimization (e.g. B0 homogenization), 2) MRS sequences for metabolic profiling, and 3) spectral processing and quantification strategies that allowed us to establish in vivo MRS as a reliable tool for translational and clinical research at Columbia University. Emphasis will be given to freeware MRS sequences and software tools that we made available to the MRS community.

ABOUT THE SPEAKER

Christoph Juchem, PhD
Columbia University Department of Biomedical Engineering

I am Associate Professor in the Departments of Biomedical Engineering and Radiology at Columbia University. In my research, I develop novel magnetic resonance methods and technology to establish optimized tools for neuroscientific and clinical applications. My long-term goal as a physicist is to realize the full potential of magnetic resonance imaging and spectroscopy as diagnostic tools. My clinical long-term goal is to understand the role that neurochemicals play in the protection of the human central nervous system (CNS) or, alternatively, how dysfunction promotes vulnerability towards psychiatric, neurodegenerative and neuro-immunological diseases.
I have 18 years of experience in developing and conducting in vivo MR experiments at 3.0-11.7 Tesla in humans and animal models (mouse, rat, non-human primate) and have demonstrated my scientific expertise in 45+ publications, book chapters and patents, as reviewer for 18 scientific journals and as grant reviewer for 7 national research societies including NIH. I served as Co-Director of Yale University's 7T Brain MR Spectroscopy Core (2010-2016), Chair of the ISMRM Engineering Study group (2014-2015), member of the ISMRM Annual Meeting Program Committee (AMPC, 2016-2019), and I serve on the editorial board of NMR in Biomedicine.

RSVP at the link above!