Columbia BME's NIH-funded T32 training program will establish a unique training paradigm in musculoskeletal disease with the following components:
Musculoskeletal diseases and injuries continue to be the leading causes of disability worldwide, imposing an enormous socioeconomic burden on the health care system in this country. This era has also ushered in paradigm-shifting scientific revolutions in tissue engineering and regenerative medicine, in vivo and ex vivo disease modeling, sequencing and genomics, high-resolution imaging, and biomechanics. These developments at the bench side require multidisciplinary expertise in science, engineering, and medicine to continue accelerating the trajectory of musculoskeletal research to address unmet clinical needs at the bedside ultimately.
However, research training in musculoskeletal research continues to be largely siloed into single-discipline approaches and settings. The Integrated Musculoskeletal Training Program (IMTP) brings together world-leading musculoskeletal researchers and clinicians at Columbia University with expertise in biomedical engineering, cell and molecular biology, pathology and cell biology, mechanical engineering, and innovation. This unique predoctoral training program focuses on integrating the multiple disciplines required for cutting-edge research training of the next generation of scientists and engineers in the field.
This T32 training program will provide a unique and timely opportunity to promote, enhance, and deepen multidisciplinary musculoskeletal research by supporting trainees with the skills and values needed to enter the biomedical research workforce and to solve the complex problems of musculoskeletal disease in the future.
Each selected trainee will be eligible to receive up to two years of support. For each year of support, NIH provides $27,144 for the predoctoral stipend, $9,600 for tuition & fees, $1,000 for trainee travel, and $2,500 for childcare costs, as per NIH NRSA Policy for FY23. Additional funds to supplement the NIH NRSA level of trainee stipend and to conduct the proposed research will be provided by the IMTP training faculty/thesis advisor.
Trainee must:
Name | Degree(s) | Rank | Primary Department or Program | Research Interest |
Agrawal, Sunil | PhD | Prof. | Mechanical Engineering | Robotics, Biomechanics |
Arinzeh, Treena | PhD | Prof. | Biomedical Engineering | Biomaterial & Tissue Engineering |
Ateshian, Gerard | PhD | Prof. | Mechanical Engineering | Cartilage Mechanics, Tissue Engineering |
Bathon, Joan | MD | Prof. | Medicine, Rheumatology | Rheumatoid Arthritis |
Chahine, Nadeen | PhD | Assoc. Prof. | Orthopedic Surgery | Intervertebral Disc, Mechanobiology, Disease Modeling, Tissue Engineering |
| Cohen, Adi | MD, MHSc | Assoc. Prof. | Medicine, Endocrinology | Osteoporosis, Bone Metabolism, Premenopausal Women |
Ducy, Patricia | PhD | Assoc. Prof. | Pathology & Cell Biology | Crosstalk, Skeleton, Brain, Pancreas |
Embree, Mildred | DMD, PhD | Asst. Prof. | College of Dental Medicine | Cartilage Biology, Osteoarthritis, Stem Cells, Regeneration |
| Giles, Jon | MD, MPH | Assoc. Prof. | Medicine, Rheumatology | Inflammatory Arthritis |
Guo, Edward | PhD | Prof. & Chair | Biomedical Engineering | Bone Biomechanics, Imaging |
Huang, Alice | PhD | Assoc. Prof. | Orthopedic Surgery | Tendon Development, Regeneration, Biology & Bioengineering |
Hung, Clark | PhD | Prof. | Biomedical Engineering | Cartilage Mechanobiology, Biomechanics, Tissue engineering |
Jaramillo, Diego | MD MPH | Prof. | Radiology | Pediatric Musculoskeletal Imaging |
Karsenty, Gerard | MD, PhD | Prof. & Chair | Genetics & Development | Skeletal Biology, Development, Physiology, Genetics |
Kousteni, Stavroula | PhD | Prof. | Physiology & Cellular Biophysics | Skeletal Functions in Metabolism & Hematopoiesis |
Lee, Chang | PhD | Assoc. Prof. | College of Dental Medicine | Meniscus and Tendon Regeneration |
Leong, Kam | PhD | Prof. | Biomedical Engineering | Gene Editing, Regenerative medicine, Drug and Gene Delivery |
Lu, Helen | PhD | Prof. | Biomedical Engineering | Interface Tissue Engineering, Biomimetic materials |
Nickolas, Thomas | MD, MS | Assoc. Prof | Medicine- Nephrology | Renal Osteodystrophy, Mineral and Bone Disorders |
Rubin, Mishaela | MD, MS | Assoc. Prof. | Medicine- Endocrinology | Skeletal Disease, Hypoparathyroidism, Diabetes |
Smeeton, Joanna | PhD | Asst. Prof. | Rehabilitation and Regeneration Medicine | Rehabilitation and Regeneration Medicine |
Thomopoulos, Stavros | PhD | Prof. | Orthopedic Surgery | Tendon Enthesis Development Mechanics, Regeneration |
Vunjak- Novakovic, Gordana | PhD | Prof. | Biomedical Engineering | Stem Cells, Tissue Engineering, Regenerative Medicine, ‘Organs On a Chip’ |
Worman, Howard | MD | Prof. | Pathology & Cell Biology | Nuclear Envelope and Muscular Dystrophy |
The application form will require the following attachments to be provided in PDF format:
Applications will be reviewed by the IMTP Trainee Selection Committee, and the ranking of all applications will be shared with IMTP Program Director (PD) and Associate Program Director (APD). The PD and APD will review the top-ranking proposals and make final decisions on which applicants will be supported by the T32. Committee members who are in conflict with a given application (i.e., when the applicant is from the member's lab) are excluded from discussions.
The ranking of applications will be based on the following criteria and weights:
After completing the first year on the training grant, students will be considered for renewal for a second year based on the student’s progress using the following criteria:
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X. Edward Guo, PHD | Image
Nadeen O. Chahine, PhD |